Iramil
Brand names,
Iramil
Analogs
Iramil
Brand Names Mixture
Iramil
Chemical_Formula
C19H24N2
Iramil
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Iramil
fda sheet
Iramil
msds (material safety sheet)
Iramil
Synthesis Reference
No information avaliable
Iramil
Molecular Weight
280.407 g/mol
Iramil
Melting Point
174.5 oC
Iramil
H2O Solubility
18.2 mg/L
Iramil
State
Solid
Iramil
LogP
4.184
Iramil
Dosage Forms
Tablet
Iramil
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Iramil
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Iramil
Absorption
Rapidly and well absorbed after oral administration
Iramil
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Iramil
Patient Information
Iramil
Organisms Affected
Humans and other mammals