Presamine en es it fr

Presamine Brand names, Presamine Analogs

Presamine Brand Names Mixture

  • No information avaliable

Presamine Chemical_Formula

C19H24N2

Presamine RX_link

http://www.rxlist.com/cgi/generic/imip.htm

Presamine fda sheet

Presamine FDA

Presamine msds (material safety sheet)

Presamine Synthesis Reference

No information avaliable

Presamine Molecular Weight

280.407 g/mol

Presamine Melting Point

174.5 oC

Presamine H2O Solubility

18.2 mg/L

Presamine State

Solid

Presamine LogP

4.184

Presamine Dosage Forms

Tablet

Presamine Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Presamine Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Presamine Absorption

Rapidly and well absorbed after oral administration

Presamine side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Presamine Patient Information

Presamine Organisms Affected

Humans and other mammals