PharmacyCodes



Apo-Famotidine en es it fr

Apo-Famotidine Brand names, Apo-Famotidine Analogs

Apo-Famotidine Brand Names Mixture

  • No information avaliable

Apo-Famotidine Chemical_Formula

C8H15N7O2S3

Apo-Famotidine RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Apo-Famotidine fda sheet

Apo-Famotidine FDA

Apo-Famotidine msds (material safety sheet)

Apo-Famotidine MSDS

Apo-Famotidine Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Apo-Famotidine Molecular Weight

337.449 g/mol

Apo-Famotidine Melting Point

163-164 oC

Apo-Famotidine H2O Solubility

1.1 mg/mL

Apo-Famotidine State

Solid

Apo-Famotidine LogP

-0.726

Apo-Famotidine Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Apo-Famotidine Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Apo-Famotidine Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Apo-Famotidine Absorption

The bioavailability of oral doses is 40-45%.

Apo-Famotidine side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Apo-Famotidine Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Apo-Famotidine Organisms Affected

Humans and other mammals