Famo

Famo Brand names, Famo Analogs

Famo Brand Names Mixture

No information avaliable

Famo Chemical_Formula

C₈H₁₅N₇O₂S₃

Famo RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Famo fda sheet

Famo FDA

Famo msds (material safety sheet)

Famo MSDS

Famo Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Famo Molecular Weight

337.449 g/mol

Famo Melting Point

163-164 ^oC

Famo H₂O Solubility

1.1 mg/mL

Famo State

Solid

Famo LogP

-0.726

Famo Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Famo Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Famo Pharmacology

Famotidine, a competitive histamine H₂-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Famo Absorption

The bioavailability of oral doses is 40-45%.

Famo side effects and Toxicity

Intravenous, mouse: LD₅₀ = 244.4mg/kg; Oral, mouse: LD₅₀ = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Famo Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Famo Organisms Affected

Humans and other mammals