Dibrit 40 en es it fr

Dibrit 40 Brand names, Dibrit 40 Analogs

Dibrit 40 Brand Names Mixture

  • No information avaliable

Dibrit 40 Chemical_Formula


Dibrit 40 RX_link


Dibrit 40 fda sheet

Dibrit_40 FDA

Dibrit 40 msds (material safety sheet)

Dibrit_40 MSDS

Dibrit 40 Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Dibrit 40 Molecular Weight

337.449 g/mol

Dibrit 40 Melting Point

163-164 oC

Dibrit 40 H2O Solubility

1.1 mg/mL

Dibrit 40 State


Dibrit 40 LogP


Dibrit 40 Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Dibrit 40 Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Dibrit 40 Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Dibrit 40 Absorption

The bioavailability of oral doses is 40-45%.

Dibrit 40 side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Dibrit 40 Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Dibrit 40 Organisms Affected

Humans and other mammals