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Famocid Brand names, Famocid Analogs

Famocid Brand Names Mixture

  • No information avaliable

Famocid Chemical_Formula

C8H15N7O2S3

Famocid RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Famocid fda sheet

Famocid FDA

Famocid msds (material safety sheet)

Famocid MSDS

Famocid Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Famocid Molecular Weight

337.449 g/mol

Famocid Melting Point

163-164 oC

Famocid H2O Solubility

1.1 mg/mL

Famocid State

Solid

Famocid LogP

-0.726

Famocid Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Famocid Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Famocid Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Famocid Absorption

The bioavailability of oral doses is 40-45%.

Famocid side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Famocid Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Famocid Organisms Affected

Humans and other mammals