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Pepcidina Brand names, Pepcidina Analogs

Pepcidina Brand Names Mixture

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Pepcidina Chemical_Formula


Pepcidina RX_link

Pepcidina fda sheet

Pepcidina FDA

Pepcidina msds (material safety sheet)

Pepcidina MSDS

Pepcidina Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Pepcidina Molecular Weight

337.449 g/mol

Pepcidina Melting Point

163-164 oC

Pepcidina H2O Solubility

1.1 mg/mL

Pepcidina State


Pepcidina LogP


Pepcidina Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Pepcidina Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Pepcidina Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Pepcidina Absorption

The bioavailability of oral doses is 40-45%.

Pepcidina side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Pepcidina Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Pepcidina Organisms Affected

Humans and other mammals