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Pepdul Brand names, Pepdul Analogs

Pepdul Brand Names Mixture

  • No information avaliable

Pepdul Chemical_Formula


Pepdul RX_link

Pepdul fda sheet

Pepdul FDA

Pepdul msds (material safety sheet)

Pepdul MSDS

Pepdul Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Pepdul Molecular Weight

337.449 g/mol

Pepdul Melting Point

163-164 oC

Pepdul H2O Solubility

1.1 mg/mL

Pepdul State


Pepdul LogP


Pepdul Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Pepdul Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Pepdul Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Pepdul Absorption

The bioavailability of oral doses is 40-45%.

Pepdul side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Pepdul Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Pepdul Organisms Affected

Humans and other mammals