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Fudone Brand names, Fudone Analogs

Fudone Brand Names Mixture

  • No information avaliable

Fudone Chemical_Formula


Fudone RX_link


Fudone fda sheet

Fudone FDA

Fudone msds (material safety sheet)

Fudone MSDS

Fudone Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Fudone Molecular Weight

337.449 g/mol

Fudone Melting Point

163-164 oC

Fudone H2O Solubility

1.1 mg/mL

Fudone State


Fudone LogP


Fudone Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Fudone Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Fudone Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Fudone Absorption

The bioavailability of oral doses is 40-45%.

Fudone side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Fudone Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Fudone Organisms Affected

Humans and other mammals