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Pepcidin Brand names, Pepcidin Analogs

Pepcidin Brand Names Mixture

  • No information avaliable

Pepcidin Chemical_Formula


Pepcidin RX_link

Pepcidin fda sheet

Pepcidin FDA

Pepcidin msds (material safety sheet)

Pepcidin MSDS

Pepcidin Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Pepcidin Molecular Weight

337.449 g/mol

Pepcidin Melting Point

163-164 oC

Pepcidin H2O Solubility

1.1 mg/mL

Pepcidin State


Pepcidin LogP


Pepcidin Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Pepcidin Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Pepcidin Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Pepcidin Absorption

The bioavailability of oral doses is 40-45%.

Pepcidin side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Pepcidin Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Pepcidin Organisms Affected

Humans and other mammals