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Fluxid Brand names, Fluxid Analogs

Fluxid Brand Names Mixture

  • No information avaliable

Fluxid Chemical_Formula

C8H15N7O2S3

Fluxid RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Fluxid fda sheet

Fluxid FDA

Fluxid msds (material safety sheet)

Fluxid MSDS

Fluxid Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Fluxid Molecular Weight

337.449 g/mol

Fluxid Melting Point

163-164 oC

Fluxid H2O Solubility

1.1 mg/mL

Fluxid State

Solid

Fluxid LogP

-0.726

Fluxid Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Fluxid Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Fluxid Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Fluxid Absorption

The bioavailability of oral doses is 40-45%.

Fluxid side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Fluxid Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Fluxid Organisms Affected

Humans and other mammals