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Motiax Brand names, Motiax Analogs

Motiax Brand Names Mixture

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Motiax Chemical_Formula


Motiax RX_link

Motiax fda sheet

Motiax FDA

Motiax msds (material safety sheet)

Motiax MSDS

Motiax Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Motiax Molecular Weight

337.449 g/mol

Motiax Melting Point

163-164 oC

Motiax H2O Solubility

1.1 mg/mL

Motiax State


Motiax LogP


Motiax Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Motiax Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Motiax Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Motiax Absorption

The bioavailability of oral doses is 40-45%.

Motiax side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Motiax Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Motiax Organisms Affected

Humans and other mammals