Purifam
Purifam Brand names, Purifam Analogs
- Amfamox
- Antodine
- Apo-Famotidine
- Apogastine
- Bestidine
- Blocacid
- Brolin
- Cepal
- Confobos
- Cronol
- Cuantin
- Dibrit 40
- Digervin
- Dinul
- Dipsin
- Dispromil
- Dispronil
- Duovel
- Durater
- Evatin
- Fadin
- Fadine
- Fadyn
- Fagastine
- Famo
- Famocid
- Famodar
- Famodil
- Famodin
- Famodine
- Famogard
- Famonit
- Famopsin
- Famos
- Famosan
- Famotal
- Famotep
- Famotidina [Spanish]
- Famotidinum [Latin]
- Famotin
- Famovane
- Famowal
- Famox
- Famoxal
- Famtac
- Famulcer
- Fanobel
- Fanosin
- Fanox
- Farmotex
- Ferotine
- Fibonel
- Fluxid
- Fudone
- Ganor
- Gaster
- Gastridan
- Gastridin
- Gastrion
- Gastro
- Gastrodomina
- Gastrofam
- Gastropen
- Gastrosidin
- H2 Bloc
- Hacip
- Huberdina
- Ingastri
- Invigan
- Lecedil
- Logos
- Mensoma
- Midefam
- Mosul
- Motiax
- Muclox
- Mylanta AR
- Neocidine
- Nevofam
- Notidin
- Novo-Famotidine
- Nu-Famotidine
- Nulceran
- Nulcerin
- Panalba
- Pepcid
- Pepcid AC
- Pepcid Ac (geltab)
- Pepcid RPD
- Pepcidin
- Pepcidin Rapitab
- Pepcidina
- Pepcidine
- Pepdif
- Pepdine
- Pepdul
- Pepfamin
- Peptan
- Peptidin
- Peptifam
- Pepzan
- Purifam
- Quamatel
- Quamtel
- Renapepsa
- Restadin
- Rogasti
- Rubacina
- Sedanium-R
- Sigafam
- Supertidine
- Tairal
- Tamin
- Tipodex
- Topcid
- Ulcatif
- Ulceprax
- Ulcofam
- Ulfagel
- Ulfam
- Ulfamid
- Ulfinol
- Ulgarine
- Vagostal
- Weimok
- Whitidin
- Yamarin
Purifam Brand Names Mixture
- No information avaliable
Purifam Chemical_Formula
C8H15N7O2S3
Purifam RX_link
http://www.rxlist.com/cgi/generic/famot.htm
Purifam fda sheet
Purifam msds (material safety sheet)
Purifam Synthesis Reference
H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)
Purifam Molecular Weight
337.449 g/mol
Purifam Melting Point
163-164 oC
Purifam H2O Solubility
1.1 mg/mL
Purifam State
Solid
Purifam LogP
-0.726
Purifam Dosage Forms
Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution
Purifam Indication
For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
Purifam Pharmacology
Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Purifam Absorption
The bioavailability of oral doses is 40-45%.
Purifam side effects and Toxicity
Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.
Purifam Patient Information
Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.
Purifam Organisms Affected
Humans and other mammals
