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Brolin Brand names, Brolin Analogs

Brolin Brand Names Mixture

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Brolin Chemical_Formula


Brolin RX_link

Brolin fda sheet

Brolin FDA

Brolin msds (material safety sheet)

Brolin MSDS

Brolin Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Brolin Molecular Weight

337.449 g/mol

Brolin Melting Point

163-164 oC

Brolin H2O Solubility

1.1 mg/mL

Brolin State


Brolin LogP


Brolin Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Brolin Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Brolin Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Brolin Absorption

The bioavailability of oral doses is 40-45%.

Brolin side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Brolin Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Brolin Organisms Affected

Humans and other mammals