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Quamatel Brand names, Quamatel Analogs

Quamatel Brand Names Mixture

  • No information avaliable

Quamatel Chemical_Formula

C8H15N7O2S3

Quamatel RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Quamatel fda sheet

Quamatel FDA

Quamatel msds (material safety sheet)

Quamatel MSDS

Quamatel Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Quamatel Molecular Weight

337.449 g/mol

Quamatel Melting Point

163-164 oC

Quamatel H2O Solubility

1.1 mg/mL

Quamatel State

Solid

Quamatel LogP

-0.726

Quamatel Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Quamatel Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Quamatel Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Quamatel Absorption

The bioavailability of oral doses is 40-45%.

Quamatel side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Quamatel Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Quamatel Organisms Affected

Humans and other mammals