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Peptan Brand names, Peptan Analogs

Peptan Brand Names Mixture

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Peptan Chemical_Formula


Peptan RX_link

Peptan fda sheet

Peptan FDA

Peptan msds (material safety sheet)

Peptan MSDS

Peptan Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Peptan Molecular Weight

337.449 g/mol

Peptan Melting Point

163-164 oC

Peptan H2O Solubility

1.1 mg/mL

Peptan State


Peptan LogP


Peptan Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Peptan Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Peptan Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Peptan Absorption

The bioavailability of oral doses is 40-45%.

Peptan side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Peptan Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Peptan Organisms Affected

Humans and other mammals