Famotal

Famotal Brand names, Famotal Analogs

Famotal Brand Names Mixture

No information avaliable

Famotal Chemical_Formula

C₈H₁₅N₇O₂S₃

Famotal RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Famotal fda sheet

Famotal FDA

Famotal msds (material safety sheet)

Famotal MSDS

Famotal Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Famotal Molecular Weight

337.449 g/mol

Famotal Melting Point

163-164 ^oC

Famotal H₂O Solubility

1.1 mg/mL

Famotal State

Solid

Famotal LogP

-0.726

Famotal Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Famotal Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Famotal Pharmacology

Famotidine, a competitive histamine H₂-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Famotal Absorption

The bioavailability of oral doses is 40-45%.

Famotal side effects and Toxicity

Intravenous, mouse: LD₅₀ = 244.4mg/kg; Oral, mouse: LD₅₀ = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Famotal Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Famotal Organisms Affected

Humans and other mammals