Pepcid AC en es it fr

Pepcid AC Brand names, Pepcid AC Analogs

Pepcid AC Brand Names Mixture

  • No information avaliable

Pepcid AC Chemical_Formula


Pepcid AC RX_link

Pepcid AC fda sheet

Pepcid_AC FDA

Pepcid AC msds (material safety sheet)

Pepcid_AC MSDS

Pepcid AC Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Pepcid AC Molecular Weight

337.449 g/mol

Pepcid AC Melting Point

163-164 oC

Pepcid AC H2O Solubility

1.1 mg/mL

Pepcid AC State


Pepcid AC LogP


Pepcid AC Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Pepcid AC Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Pepcid AC Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Pepcid AC Absorption

The bioavailability of oral doses is 40-45%.

Pepcid AC side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Pepcid AC Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Pepcid AC Organisms Affected

Humans and other mammals