Supertidine en es it fr

Supertidine Brand names, Supertidine Analogs

Supertidine Brand Names Mixture

  • No information avaliable

Supertidine Chemical_Formula


Supertidine RX_link

Supertidine fda sheet

Supertidine FDA

Supertidine msds (material safety sheet)

Supertidine MSDS

Supertidine Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Supertidine Molecular Weight

337.449 g/mol

Supertidine Melting Point

163-164 oC

Supertidine H2O Solubility

1.1 mg/mL

Supertidine State


Supertidine LogP


Supertidine Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Supertidine Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Supertidine Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Supertidine Absorption

The bioavailability of oral doses is 40-45%.

Supertidine side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Supertidine Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Supertidine Organisms Affected

Humans and other mammals