Sigafam
Sigafam Brand names, Sigafam Analogs
- Amfamox
- Antodine
- Apo-Famotidine
- Apogastine
- Bestidine
- Blocacid
- Brolin
- Cepal
- Confobos
- Cronol
- Cuantin
- Dibrit 40
- Digervin
- Dinul
- Dipsin
- Dispromil
- Dispronil
- Duovel
- Durater
- Evatin
- Fadin
- Fadine
- Fadyn
- Fagastine
- Famo
- Famocid
- Famodar
- Famodil
- Famodin
- Famodine
- Famogard
- Famonit
- Famopsin
- Famos
- Famosan
- Famotal
- Famotep
- Famotidina [Spanish]
- Famotidinum [Latin]
- Famotin
- Famovane
- Famowal
- Famox
- Famoxal
- Famtac
- Famulcer
- Fanobel
- Fanosin
- Fanox
- Farmotex
- Ferotine
- Fibonel
- Fluxid
- Fudone
- Ganor
- Gaster
- Gastridan
- Gastridin
- Gastrion
- Gastro
- Gastrodomina
- Gastrofam
- Gastropen
- Gastrosidin
- H2 Bloc
- Hacip
- Huberdina
- Ingastri
- Invigan
- Lecedil
- Logos
- Mensoma
- Midefam
- Mosul
- Motiax
- Muclox
- Mylanta AR
- Neocidine
- Nevofam
- Notidin
- Novo-Famotidine
- Nu-Famotidine
- Nulceran
- Nulcerin
- Panalba
- Pepcid
- Pepcid AC
- Pepcid Ac (geltab)
- Pepcid RPD
- Pepcidin
- Pepcidin Rapitab
- Pepcidina
- Pepcidine
- Pepdif
- Pepdine
- Pepdul
- Pepfamin
- Peptan
- Peptidin
- Peptifam
- Pepzan
- Purifam
- Quamatel
- Quamtel
- Renapepsa
- Restadin
- Rogasti
- Rubacina
- Sedanium-R
- Sigafam
- Supertidine
- Tairal
- Tamin
- Tipodex
- Topcid
- Ulcatif
- Ulceprax
- Ulcofam
- Ulfagel
- Ulfam
- Ulfamid
- Ulfinol
- Ulgarine
- Vagostal
- Weimok
- Whitidin
- Yamarin
Sigafam Brand Names Mixture
- No information avaliable
Sigafam Chemical_Formula
C8H15N7O2S3
Sigafam RX_link
http://www.rxlist.com/cgi/generic/famot.htm
Sigafam fda sheet
Sigafam msds (material safety sheet)
Sigafam Synthesis Reference
H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)
Sigafam Molecular Weight
337.449 g/mol
Sigafam Melting Point
163-164 oC
Sigafam H2O Solubility
1.1 mg/mL
Sigafam State
Solid
Sigafam LogP
-0.726
Sigafam Dosage Forms
Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution
Sigafam Indication
For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
Sigafam Pharmacology
Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Sigafam Absorption
The bioavailability of oral doses is 40-45%.
Sigafam side effects and Toxicity
Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.
Sigafam Patient Information
Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.
Sigafam Organisms Affected
Humans and other mammals
