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Rubacina Brand names, Rubacina Analogs

Rubacina Brand Names Mixture

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Rubacina Chemical_Formula


Rubacina RX_link

Rubacina fda sheet

Rubacina FDA

Rubacina msds (material safety sheet)

Rubacina MSDS

Rubacina Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Rubacina Molecular Weight

337.449 g/mol

Rubacina Melting Point

163-164 oC

Rubacina H2O Solubility

1.1 mg/mL

Rubacina State


Rubacina LogP


Rubacina Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Rubacina Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Rubacina Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Rubacina Absorption

The bioavailability of oral doses is 40-45%.

Rubacina side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Rubacina Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Rubacina Organisms Affected

Humans and other mammals