Remsed Brand names, Remsed Analogs
Remsed Brand Names Mixture
- Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)
Remsed fda sheet
Remsed msds (material safety sheet)
Remsed Synthesis Reference
Charpentier, U.S. Pat. 2,503,451 (1950)
Remsed Molecular Weight
Remsed Melting Point
Remsed H2O Solubility
Remsed Dosage Forms
Tablet; Suppository; Opthalmic drops; Syrup
For the treatment of allergic disorders, itching, nausea and vomiting.
Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.
Remsed side effects and Toxicity
Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)
Remsed Patient Information
Remsed Organisms Affected
Humans and other mammals