Mymethazine Fortis
Category
Mymethazine Fortis Brand names, Mymethazine Fortis Analogs
Mymethazine Fortis Brand Names Mixture
- Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)
Mymethazine Fortis Chemical_Formula
C17H20N2S
Mymethazine Fortis RX_link
http://www.rxlist.com/cgi/generic3/phenergan.htm
Mymethazine Fortis fda sheet
Mymethazine Fortis msds (material safety sheet)
Mymethazine Fortis Synthesis Reference
Charpentier, U.S. Pat. 2,503,451 (1950)
Mymethazine Fortis Molecular Weight
284.42 g/mol
Mymethazine Fortis Melting Point
60oC
Mymethazine Fortis H2O Solubility
Freely soluble
Mymethazine Fortis State
Solid
Mymethazine Fortis LogP
4.946
Mymethazine Fortis Dosage Forms
Tablet; Suppository; Opthalmic drops; Syrup
Mymethazine Fortis Indication
For the treatment of allergic disorders, itching, nausea and vomiting.
Mymethazine Fortis Pharmacology
Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
Mymethazine Fortis Absorption
On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.
Mymethazine Fortis side effects and Toxicity
Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)
Mymethazine Fortis Patient Information
Mymethazine Fortis Organisms Affected
Humans and other mammals
