Phenergan Fortis
Category
Phenergan Fortis Brand names, Phenergan Fortis Analogs
Phenergan Fortis Brand Names Mixture
- Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)
Phenergan Fortis Chemical_Formula
C17H20N2S
Phenergan Fortis RX_link
http://www.rxlist.com/cgi/generic3/phenergan.htm
Phenergan Fortis fda sheet
Phenergan Fortis msds (material safety sheet)
Phenergan Fortis Synthesis Reference
Charpentier, U.S. Pat. 2,503,451 (1950)
Phenergan Fortis Molecular Weight
284.42 g/mol
Phenergan Fortis Melting Point
60oC
Phenergan Fortis H2O Solubility
Freely soluble
Phenergan Fortis State
Solid
Phenergan Fortis LogP
4.946
Phenergan Fortis Dosage Forms
Tablet; Suppository; Opthalmic drops; Syrup
Phenergan Fortis Indication
For the treatment of allergic disorders, itching, nausea and vomiting.
Phenergan Fortis Pharmacology
Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
Phenergan Fortis Absorption
On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.
Phenergan Fortis side effects and Toxicity
Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)
Phenergan Fortis Patient Information
Phenergan Fortis Organisms Affected
Humans and other mammals
