Fenetazina Brand names, Fenetazina Analogs
Fenetazina Brand Names Mixture
- Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)
Fenetazina fda sheet
Fenetazina msds (material safety sheet)
Fenetazina Synthesis Reference
Charpentier, U.S. Pat. 2,503,451 (1950)
Fenetazina Molecular Weight
Fenetazina Melting Point
Fenetazina H2O Solubility
Fenetazina Dosage Forms
Tablet; Suppository; Opthalmic drops; Syrup
For the treatment of allergic disorders, itching, nausea and vomiting.
Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.
Fenetazina side effects and Toxicity
Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)
Fenetazina Patient Information
Fenetazina Organisms Affected
Humans and other mammals