Fenetazina
Fenetazina Brand names, Fenetazina Analogs
- Allergan
- Aprobit
- Atosil
- Avomine
- Dimapp
- Diphergan
- Diprazine
- Diprozin
- Dorme
- Duplamin
- Fargan
- Fellozine
- Fenazil
- Fenergan
- Fenetazina
- Genphen
- Hiberna
- Histargan
- Iergigan
- Isophenergan
- Isopromethazine
- Lercigan
- Lergigan
- Lilly 1516
- Mymethazine Fortis
- Phargan
- Phenargan
- Phencen
- Phenergan
- Phenergan Fortis
- Phensedyl
- Pilpophen
- Pipolphen
- Proazaimine
- Proazamine
- Procit
- Promazinamide
- Prometasin
- Prometazin
- Prometh Fortis
- Prometh Plain
- Promethacon
- Promethaine
- Promethazin
- Promethazine Hcl
- Promethazine Plain
- Promethegan
- Promethiazine
- Promezathine
- Prorex
- Protazine
- Prothazin
- Prothazine
- Provigan
- Pyrethia
- Pyrethiazine
- Remsed
- Romergan
- Synalgos
- Tanidil
- Thiergan
- Valergine
- Vallergine
- Zipan-25
Fenetazina Brand Names Mixture
- Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)
Fenetazina Chemical_Formula
C17H20N2S
Fenetazina RX_link
http://www.rxlist.com/cgi/generic3/phenergan.htm
Fenetazina fda sheet
Fenetazina msds (material safety sheet)
Fenetazina Synthesis Reference
Charpentier, U.S. Pat. 2,503,451 (1950)
Fenetazina Molecular Weight
284.42 g/mol
Fenetazina Melting Point
60oC
Fenetazina H2O Solubility
Freely soluble
Fenetazina State
Solid
Fenetazina LogP
4.946
Fenetazina Dosage Forms
Tablet; Suppository; Opthalmic drops; Syrup
Fenetazina Indication
For the treatment of allergic disorders, itching, nausea and vomiting.
Fenetazina Pharmacology
Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
Fenetazina Absorption
On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.
Fenetazina side effects and Toxicity
Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)
Fenetazina Patient Information
Fenetazina Organisms Affected
Humans and other mammals
