Pasolac
Pasolac Brand names, Pasolac Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pasolac Brand Names Mixture
- No information avaliable
Pasolac Chemical_Formula
C7H7NO3
Pasolac RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pasolac fda sheet
Pasolac msds (material safety sheet)
Pasolac Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pasolac Molecular Weight
153.135 g/mol
Pasolac Melting Point
150.5 oC
Pasolac H2O Solubility
1690 mg/L
Pasolac State
Solid
Pasolac LogP
1.012
Pasolac Dosage Forms
Packet of coated granules
Pasolac Indication
For the treatment of tuberculosis
Pasolac Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pasolac Absorption
No information avaliable
Pasolac side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pasolac Patient Information
Pasolac Organisms Affected
Mycobacteria
