Para-Amino Salicylic Acid

Para-Amino Salicylic Acid Brand names, Para-Amino Salicylic Acid Analogs

Para-Amino Salicylic Acid Brand Names Mixture

No information avaliable

Para-Amino Salicylic Acid Chemical_Formula

C₇H₇NO₃

Para-Amino Salicylic Acid RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Para-Amino Salicylic Acid fda sheet

Para-Amino Salicylic Acid msds (material safety sheet)

Para-Amino_Salicylic_Acid MSDS

Para-Amino Salicylic Acid Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Para-Amino Salicylic Acid Molecular Weight

153.135 g/mol

Para-Amino Salicylic Acid Melting Point

150.5 ^oC

Para-Amino Salicylic Acid H₂O Solubility

1690 mg/L

Para-Amino Salicylic Acid State

Solid

Para-Amino Salicylic Acid LogP

1.012

Para-Amino Salicylic Acid Dosage Forms

Packet of coated granules

Para-Amino Salicylic Acid Indication

For the treatment of tuberculosis

Para-Amino Salicylic Acid Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Para-Amino Salicylic Acid Absorption

No information avaliable

Para-Amino Salicylic Acid side effects and Toxicity

LD₅₀=4 gm/kg (orally in mice); LD₅₀=3650 mg/kg (orally in rabbits)

Para-Amino Salicylic Acid Patient Information

Para-Amino Salicylic Acid Organisms Affected

Mycobacteria