Pasem
Pasem Brand names, Pasem Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pasem Brand Names Mixture
- No information avaliable
Pasem Chemical_Formula
C7H7NO3
Pasem RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pasem fda sheet
Pasem msds (material safety sheet)
Pasem Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pasem Molecular Weight
153.135 g/mol
Pasem Melting Point
150.5 oC
Pasem H2O Solubility
1690 mg/L
Pasem State
Solid
Pasem LogP
1.012
Pasem Dosage Forms
Packet of coated granules
Pasem Indication
For the treatment of tuberculosis
Pasem Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pasem Absorption
No information avaliable
Pasem side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pasem Patient Information
Pasem Organisms Affected
Mycobacteria
