PASK
PASK Brand names, PASK Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
PASK Brand Names Mixture
- No information avaliable
PASK Chemical_Formula
C7H7NO3
PASK RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
PASK fda sheet
PASK msds (material safety sheet)
PASK Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
PASK Molecular Weight
153.135 g/mol
PASK Melting Point
150.5 oC
PASK H2O Solubility
1690 mg/L
PASK State
Solid
PASK LogP
1.012
PASK Dosage Forms
Packet of coated granules
PASK Indication
For the treatment of tuberculosis
PASK Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
PASK Absorption
No information avaliable
PASK side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
PASK Patient Information
PASK Organisms Affected
Mycobacteria
