Entepas
Entepas Brand names, Entepas Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Entepas Brand Names Mixture
- No information avaliable
Entepas Chemical_Formula
C7H7NO3
Entepas RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Entepas fda sheet
Entepas msds (material safety sheet)
Entepas Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Entepas Molecular Weight
153.135 g/mol
Entepas Melting Point
150.5 oC
Entepas H2O Solubility
1690 mg/L
Entepas State
Solid
Entepas LogP
1.012
Entepas Dosage Forms
Packet of coated granules
Entepas Indication
For the treatment of tuberculosis
Entepas Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Entepas Absorption
No information avaliable
Entepas side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Entepas Patient Information
Entepas Organisms Affected
Mycobacteria
