Pamacyl
Pamacyl Brand names, Pamacyl Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pamacyl Brand Names Mixture
- No information avaliable
Pamacyl Chemical_Formula
C7H7NO3
Pamacyl RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pamacyl fda sheet
Pamacyl msds (material safety sheet)
Pamacyl Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pamacyl Molecular Weight
153.135 g/mol
Pamacyl Melting Point
150.5 oC
Pamacyl H2O Solubility
1690 mg/L
Pamacyl State
Solid
Pamacyl LogP
1.012
Pamacyl Dosage Forms
Packet of coated granules
Pamacyl Indication
For the treatment of tuberculosis
Pamacyl Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pamacyl Absorption
No information avaliable
Pamacyl side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pamacyl Patient Information
Pamacyl Organisms Affected
Mycobacteria
