Pasmed
Pasmed Brand names, Pasmed Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pasmed Brand Names Mixture
- No information avaliable
Pasmed Chemical_Formula
C7H7NO3
Pasmed RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pasmed fda sheet
Pasmed msds (material safety sheet)
Pasmed Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pasmed Molecular Weight
153.135 g/mol
Pasmed Melting Point
150.5 oC
Pasmed H2O Solubility
1690 mg/L
Pasmed State
Solid
Pasmed LogP
1.012
Pasmed Dosage Forms
Packet of coated granules
Pasmed Indication
For the treatment of tuberculosis
Pasmed Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pasmed Absorption
No information avaliable
Pasmed side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pasmed Patient Information
Pasmed Organisms Affected
Mycobacteria
