Parasalindon
Brand names,
Parasalindon
Analogs
Parasalindon
Brand Names Mixture
Parasalindon
Chemical_Formula
C7H7NO3
Parasalindon
RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Parasalindon
fda sheet
Parasalindon
msds (material safety sheet)
Parasalindon
Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Parasalindon
Molecular Weight
153.135 g/mol
Parasalindon
Melting Point
150.5 oC
Parasalindon
H2O Solubility
1690 mg/L
Parasalindon
State
Solid
Parasalindon
LogP
1.012
Parasalindon
Dosage Forms
Packet of coated granules
Parasalindon
Indication
For the treatment of tuberculosis
Parasalindon
Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Parasalindon
Absorption
No information avaliable
Parasalindon
side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Parasalindon
Patient Information
Parasalindon
Organisms Affected
Mycobacteria