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Apas Brand names, Apas Analogs

Apas Brand Names Mixture

  • No information avaliable

Apas Chemical_Formula


Apas RX_link


Apas fda sheet

Apas msds (material safety sheet)


Apas Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Apas Molecular Weight

153.135 g/mol

Apas Melting Point

150.5 oC

Apas H2O Solubility

1690 mg/L

Apas State


Apas LogP


Apas Dosage Forms

Packet of coated granules

Apas Indication

For the treatment of tuberculosis

Apas Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Apas Absorption

No information avaliable

Apas side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Apas Patient Information

Apas Organisms Affected