Apas
Apas Brand names, Apas Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Apas Brand Names Mixture
- No information avaliable
Apas Chemical_Formula
C7H7NO3
Apas RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Apas fda sheet
Apas msds (material safety sheet)
Apas Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Apas Molecular Weight
153.135 g/mol
Apas Melting Point
150.5 oC
Apas H2O Solubility
1690 mg/L
Apas State
Solid
Apas LogP
1.012
Apas Dosage Forms
Packet of coated granules
Apas Indication
For the treatment of tuberculosis
Apas Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Apas Absorption
No information avaliable
Apas side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Apas Patient Information
Apas Organisms Affected
Mycobacteria
