PAS-C
PAS-C Brand names, PAS-C Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
PAS-C Brand Names Mixture
- No information avaliable
PAS-C Chemical_Formula
C7H7NO3
PAS-C RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
PAS-C fda sheet
PAS-C msds (material safety sheet)
PAS-C Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
PAS-C Molecular Weight
153.135 g/mol
PAS-C Melting Point
150.5 oC
PAS-C H2O Solubility
1690 mg/L
PAS-C State
Solid
PAS-C LogP
1.012
PAS-C Dosage Forms
Packet of coated granules
PAS-C Indication
For the treatment of tuberculosis
PAS-C Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
PAS-C Absorption
No information avaliable
PAS-C side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
PAS-C Patient Information
PAS-C Organisms Affected
Mycobacteria
