Pasnodia
Brand names,
Pasnodia
Analogs
Pasnodia
Brand Names Mixture
Pasnodia
Chemical_Formula
C7H7NO3
Pasnodia
RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pasnodia
fda sheet
Pasnodia
msds (material safety sheet)
Pasnodia
Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pasnodia
Molecular Weight
153.135 g/mol
Pasnodia
Melting Point
150.5 oC
Pasnodia
H2O Solubility
1690 mg/L
Pasnodia
State
Solid
Pasnodia
LogP
1.012
Pasnodia
Dosage Forms
Packet of coated granules
Pasnodia
Indication
For the treatment of tuberculosis
Pasnodia
Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pasnodia
Absorption
No information avaliable
Pasnodia
side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pasnodia
Patient Information
Pasnodia
Organisms Affected
Mycobacteria