Hellipidyl
Brand names,
Hellipidyl
Analogs
Hellipidyl
Brand Names Mixture
Hellipidyl
Chemical_Formula
C7H7NO3
Hellipidyl
RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Hellipidyl
fda sheet
Hellipidyl
msds (material safety sheet)
Hellipidyl
Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Hellipidyl
Molecular Weight
153.135 g/mol
Hellipidyl
Melting Point
150.5 oC
Hellipidyl
H2O Solubility
1690 mg/L
Hellipidyl
State
Solid
Hellipidyl
LogP
1.012
Hellipidyl
Dosage Forms
Packet of coated granules
Hellipidyl
Indication
For the treatment of tuberculosis
Hellipidyl
Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Hellipidyl
Absorption
No information avaliable
Hellipidyl
side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Hellipidyl
Patient Information
Hellipidyl
Organisms Affected
Mycobacteria