Pascorbic
Pascorbic Brand names, Pascorbic Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pascorbic Brand Names Mixture
- No information avaliable
Pascorbic Chemical_Formula
C7H7NO3
Pascorbic RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pascorbic fda sheet
Pascorbic msds (material safety sheet)
Pascorbic Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pascorbic Molecular Weight
153.135 g/mol
Pascorbic Melting Point
150.5 oC
Pascorbic H2O Solubility
1690 mg/L
Pascorbic State
Solid
Pascorbic LogP
1.012
Pascorbic Dosage Forms
Packet of coated granules
Pascorbic Indication
For the treatment of tuberculosis
Pascorbic Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pascorbic Absorption
No information avaliable
Pascorbic side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pascorbic Patient Information
Pascorbic Organisms Affected
Mycobacteria
