Deapasil
Brand names,
Deapasil
Analogs
Deapasil
Brand Names Mixture
Deapasil
Chemical_Formula
C7H7NO3
Deapasil
RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Deapasil
fda sheet
Deapasil
msds (material safety sheet)
Deapasil
Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Deapasil
Molecular Weight
153.135 g/mol
Deapasil
Melting Point
150.5 oC
Deapasil
H2O Solubility
1690 mg/L
Deapasil
State
Solid
Deapasil
LogP
1.012
Deapasil
Dosage Forms
Packet of coated granules
Deapasil
Indication
For the treatment of tuberculosis
Deapasil
Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Deapasil
Absorption
No information avaliable
Deapasil
side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Deapasil
Patient Information
Deapasil
Organisms Affected
Mycobacteria