Paramycin
Paramycin Brand names, Paramycin Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Paramycin Brand Names Mixture
- No information avaliable
Paramycin Chemical_Formula
C7H7NO3
Paramycin RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Paramycin fda sheet
Paramycin msds (material safety sheet)
Paramycin Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Paramycin Molecular Weight
153.135 g/mol
Paramycin Melting Point
150.5 oC
Paramycin H2O Solubility
1690 mg/L
Paramycin State
Solid
Paramycin LogP
1.012
Paramycin Dosage Forms
Packet of coated granules
Paramycin Indication
For the treatment of tuberculosis
Paramycin Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Paramycin Absorption
No information avaliable
Paramycin side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Paramycin Patient Information
Paramycin Organisms Affected
Mycobacteria
