Pamisyl
Pamisyl Brand names, Pamisyl Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pamisyl Brand Names Mixture
- No information avaliable
Pamisyl Chemical_Formula
C7H7NO3
Pamisyl RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pamisyl fda sheet
Pamisyl msds (material safety sheet)
Pamisyl Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pamisyl Molecular Weight
153.135 g/mol
Pamisyl Melting Point
150.5 oC
Pamisyl H2O Solubility
1690 mg/L
Pamisyl State
Solid
Pamisyl LogP
1.012
Pamisyl Dosage Forms
Packet of coated granules
Pamisyl Indication
For the treatment of tuberculosis
Pamisyl Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pamisyl Absorption
No information avaliable
Pamisyl side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pamisyl Patient Information
Pamisyl Organisms Affected
Mycobacteria
