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Paser Brand names, Paser Analogs

Paser Brand Names Mixture

  • No information avaliable

Paser Chemical_Formula

C7H7NO3

Paser RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Paser fda sheet

Paser msds (material safety sheet)

Paser MSDS

Paser Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Paser Molecular Weight

153.135 g/mol

Paser Melting Point

150.5 oC

Paser H2O Solubility

1690 mg/L

Paser State

Solid

Paser LogP

1.012

Paser Dosage Forms

Packet of coated granules

Paser Indication

For the treatment of tuberculosis

Paser Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Paser Absorption

No information avaliable

Paser side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Paser Patient Information

Paser Organisms Affected

Mycobacteria