Aminox
Aminox Brand names, Aminox Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Aminox Brand Names Mixture
- No information avaliable
Aminox Chemical_Formula
C7H7NO3
Aminox RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Aminox fda sheet
Aminox msds (material safety sheet)
Aminox Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Aminox Molecular Weight
153.135 g/mol
Aminox Melting Point
150.5 oC
Aminox H2O Solubility
1690 mg/L
Aminox State
Solid
Aminox LogP
1.012
Aminox Dosage Forms
Packet of coated granules
Aminox Indication
For the treatment of tuberculosis
Aminox Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Aminox Absorption
No information avaliable
Aminox side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Aminox Patient Information
Aminox Organisms Affected
Mycobacteria
