Pasdium
Pasdium Brand names, Pasdium Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pasdium Brand Names Mixture
- No information avaliable
Pasdium Chemical_Formula
C7H7NO3
Pasdium RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pasdium fda sheet
Pasdium msds (material safety sheet)
Pasdium Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pasdium Molecular Weight
153.135 g/mol
Pasdium Melting Point
150.5 oC
Pasdium H2O Solubility
1690 mg/L
Pasdium State
Solid
Pasdium LogP
1.012
Pasdium Dosage Forms
Packet of coated granules
Pasdium Indication
For the treatment of tuberculosis
Pasdium Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pasdium Absorption
No information avaliable
Pasdium side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pasdium Patient Information
Pasdium Organisms Affected
Mycobacteria
