Kyselina P-Aminosalicylova

Kyselina P-Aminosalicylova Brand names, Kyselina P-Aminosalicylova Analogs

Kyselina P-Aminosalicylova Brand Names Mixture

No information avaliable

Kyselina P-Aminosalicylova Chemical_Formula

C₇H₇NO₃

Kyselina P-Aminosalicylova RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Kyselina P-Aminosalicylova fda sheet

Kyselina P-Aminosalicylova msds (material safety sheet)

Kyselina_P-Aminosalicylova MSDS

Kyselina P-Aminosalicylova Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Kyselina P-Aminosalicylova Molecular Weight

153.135 g/mol

Kyselina P-Aminosalicylova Melting Point

150.5 ^oC

Kyselina P-Aminosalicylova H₂O Solubility

1690 mg/L

Kyselina P-Aminosalicylova State

Solid

Kyselina P-Aminosalicylova LogP

1.012

Kyselina P-Aminosalicylova Dosage Forms

Packet of coated granules

Kyselina P-Aminosalicylova Indication

For the treatment of tuberculosis

Kyselina P-Aminosalicylova Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Kyselina P-Aminosalicylova Absorption

No information avaliable

Kyselina P-Aminosalicylova side effects and Toxicity

LD₅₀=4 gm/kg (orally in mice); LD₅₀=3650 mg/kg (orally in rabbits)

Kyselina P-Aminosalicylova Patient Information

Kyselina P-Aminosalicylova Organisms Affected

Mycobacteria