Parasalicil
Parasalicil Brand names, Parasalicil Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Parasalicil Brand Names Mixture
- No information avaliable
Parasalicil Chemical_Formula
C7H7NO3
Parasalicil RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Parasalicil fda sheet
Parasalicil msds (material safety sheet)
Parasalicil Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Parasalicil Molecular Weight
153.135 g/mol
Parasalicil Melting Point
150.5 oC
Parasalicil H2O Solubility
1690 mg/L
Parasalicil State
Solid
Parasalicil LogP
1.012
Parasalicil Dosage Forms
Packet of coated granules
Parasalicil Indication
For the treatment of tuberculosis
Parasalicil Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Parasalicil Absorption
No information avaliable
Parasalicil side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Parasalicil Patient Information
Parasalicil Organisms Affected
Mycobacteria
