Aminopar
Aminopar Brand names, Aminopar Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Aminopar Brand Names Mixture
- No information avaliable
Aminopar Chemical_Formula
C7H7NO3
Aminopar RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Aminopar fda sheet
Aminopar msds (material safety sheet)
Aminopar Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Aminopar Molecular Weight
153.135 g/mol
Aminopar Melting Point
150.5 oC
Aminopar H2O Solubility
1690 mg/L
Aminopar State
Solid
Aminopar LogP
1.012
Aminopar Dosage Forms
Packet of coated granules
Aminopar Indication
For the treatment of tuberculosis
Aminopar Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Aminopar Absorption
No information avaliable
Aminopar side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Aminopar Patient Information
Aminopar Organisms Affected
Mycobacteria
