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Apacil Brand names, Apacil Analogs

Apacil Brand Names Mixture

  • No information avaliable

Apacil Chemical_Formula


Apacil RX_link


Apacil fda sheet

Apacil msds (material safety sheet)

Apacil MSDS

Apacil Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Apacil Molecular Weight

153.135 g/mol

Apacil Melting Point

150.5 oC

Apacil H2O Solubility

1690 mg/L

Apacil State


Apacil LogP


Apacil Dosage Forms

Packet of coated granules

Apacil Indication

For the treatment of tuberculosis

Apacil Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Apacil Absorption

No information avaliable

Apacil side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Apacil Patient Information

Apacil Organisms Affected