Pasara
Pasara Brand names, Pasara Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pasara Brand Names Mixture
- No information avaliable
Pasara Chemical_Formula
C7H7NO3
Pasara RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pasara fda sheet
Pasara msds (material safety sheet)
Pasara Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pasara Molecular Weight
153.135 g/mol
Pasara Melting Point
150.5 oC
Pasara H2O Solubility
1690 mg/L
Pasara State
Solid
Pasara LogP
1.012
Pasara Dosage Forms
Packet of coated granules
Pasara Indication
For the treatment of tuberculosis
Pasara Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pasara Absorption
No information avaliable
Pasara side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pasara Patient Information
Pasara Organisms Affected
Mycobacteria
