Osacyl
Osacyl Brand names, Osacyl Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Osacyl Brand Names Mixture
- No information avaliable
Osacyl Chemical_Formula
C7H7NO3
Osacyl RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Osacyl fda sheet
Osacyl msds (material safety sheet)
Osacyl Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Osacyl Molecular Weight
153.135 g/mol
Osacyl Melting Point
150.5 oC
Osacyl H2O Solubility
1690 mg/L
Osacyl State
Solid
Osacyl LogP
1.012
Osacyl Dosage Forms
Packet of coated granules
Osacyl Indication
For the treatment of tuberculosis
Osacyl Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Osacyl Absorption
No information avaliable
Osacyl side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Osacyl Patient Information
Osacyl Organisms Affected
Mycobacteria
